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Sunday, 25 June 2017

Paracetamol and pregnancy - more cautionary research (unborn son's fertility)

Yet another research paper has been published suggesting a link between paracetamol (acetaminophen) exposure during pregnancy and damage to the male reproductive system.  
http://www.reproduction-online.org/content/154/2/145.full
This study, like those done previously, involved mice but, like other similar studies, found that paracetamol interferes with testosterone production in male fetuses.  The mice in this study were given doses equivalent to the recommended dose for pregnant women.  The findings from this latest Danish study, published in "Reproduction":

"suggest that prenatal exposure to APAP [paracetamol] may impair male sexual behaviour in adulthood by disrupting the sexual neurobehavioral programming. These findings add to the growing body of evidence suggesting the need to limit the widespread exposure and use of APAP by pregnant women." 
It is worrying that advice to pregnant women experiencing common musculo-skeletal problems in pregnancy or the latent phase of labour, at least in the UK, are advised to take paracetamol with no mention of its possible side-effects (see Undercover Midwife's posts of 28.3.15 and 26.5.15).

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